Oct 26,2022 from RTVE via El Communista translation thefreeonline

An anticancer drug developed at the Vall d’Hebron Institute of Oncology (VHIO) has managed to stabilize the disease and slow down tumor growth in eight patients, according to the preliminary results of phase I clinical trials conducted on 22 people. Tests with Omomyc (OMO-103) also indicate that it has few side effects, so it will continue to be evaluated in a second phase.

Un fármaco logra estabilizar el gen más común del cáncer

First ever inhibitor of this oncogene to successfully complete a phase I clinical trial

The preliminary results will continue to be evaluated in phase II of human trials: “It is still very early.”The drug targets, for the first time, a key oncogene in tumor development and has caused few side effects.

Elena Garralda, director of the Cancer Molecular Therapy Research Unit (UITM) – CaixaResearch of the VHIO.VALL D’HEBRON INSTITUTO DE ONCOLOGÍA (VHIO)

The 22 patients who participated in the clinical trial that began in April 2021 had a variety of solid tumors, including non-small cell lung, intestine and pancreatic cancers, and had received at least three prior treatments, making them heavily pre-treated. Eight of 12 patients who underwent CT scans after nine weeks of treatment showed stable disease in which tumor growth had stopped.

“It is still too early to assess the activity of the drug, but we are seeing the stabilization of the disease in some patients. Of note is the case of a patient with pancreatic cancer who remained in the study for more than six months, and in whom the tumor shrank by 8% and there was an 83% reduction in tumor-derived DNA circulating in the bloodstream.

Laura Soucek (born 1973) is a Group Leader at VHIO (the Vall d’Hebron Institute of Oncology), Research Professor at ICREA, and CEO of Peptomyc S.L.She works on the Myc oncoprotein, the deregulation of which occurs during almost all cancers.Soucek has designed a dominant negative variant, Omomyc, which allows her to investigate the benefits of inhibiting Myc in cancer.

There is also a patient with a salivary gland tumor whose disease remains stable and is still in the study after 15 months, and a patient with sarcoma, who had responded very poorly to previous treatments, who remained stable for 8 months.” explained Dr. Elena Garralda, director of the Cancer Molecular Therapy Research Unit (UITM) – CaixaResearch of the VHIO.

These are preliminary results and will be further evaluated in a phase II clinical trial, which will begin in the coming months. Omomyc will also be tested in combination with chemotherapy or other therapies.

Masso // Dr Soutek

The MYC oncogene is on target for the first time

Omomyc is a therapeutic miniprotein that targets the MYC oncogene, deregulated in the vast majority of tumors. Until recently it was considered therapeutically unattainable, but the researchers in Barcelona previously demonstrated in the laboratory that the protein is capable of entering cells and reaching their nucleus, where the oncogene is found.

Continue reading “Barcelona: A new drug stabilizes the most common cancer gene, stops growth of cancer in eight patients – English/Español”

TEHRAN: Iranian security forces have clashed with people taking part in a memorial for Mahsa Amini, according to a semi-official news agency, as thousands gathered in her hometown of Saqqez to mark 40 days since her death.

“A limited number of those present at Mahsa Amini’s memorial clashed with police forces on the outskirts of Saqqez and were dispersed,” ISNA news agency reported on Wednesday. “Following the scattered clashes, internet in Saqqez was cut off due to security considerations.”

Amini, a 22-year-old Kurdish woman, died in the capital, Tehran, on September 16 after being detained by the country’s morality police for allegedly wearing improper hijab. Her family have challenged a state investigation that blamed pre-existing conditions for her death which, it said, was not the result of Amini being hit.

The weeks-long protests first broke out in Saqqez, in the northwestern Kurdistan province. They have since spread quickly across the country, persisting amid severe internet restrictions that remain in place.

The 40th day since someone’s funeral, known as “chehelom”, holds cultural significance in Iran and religious importance for Shia Muslims.

On Wednesday, videos circulating on social media showed large crowds marching and driving towards the Aychi cemetery in Saqqez, where Amini was laid to rest.

Those gathered included people converging from other cities and appeared to number in the thousands. Many chanted “woman, life, freedom” and “freedom, freedom”, slogans that have been widely used in the demonstrations across Iran, as well as in solidarity protests that have been organised outside the country.

Speaking from Tehran, Al Jazeera’s Dorsa Jabbari said an estimated 10,000 people were reportedly in attendance at the cemetery to pay their respects to Amini.

“Following the services that took place, when people were dispersing that’s when the disputes erupted between the people there and the security forces – as a result of which, we heard that the government there has decided to cut off the internet due to security considerations,” added Jabbari.

“That means that nearly 1.5 million people in Kurdistan province will not have access to the internet for the foreseeable future.”

Earlier on Wednesday, all schools and universities across the province had been ordered closed, with officials citing an “increase in the spread of influenza” as the reason.

There were reports that popular figures like legendary footballer Ali Daei had travelled to Saqqez for the memorial, and that authorities had closed off roads into the city, leading people to cross rivers and walk long distances to get to the cemetery, all of which were rejected by state-affiliated media.

Esmail Zarei Kousha, the governor of Kurdistan, said on Wednesday foreign-based media were trying to use Amini’s chehelom as an excuse to sow unrest.

Iran’s foreign ministry this week imposed sanctions on several Europe-based Persian-language channels for “inciting terrorism” in relation to their coverage of the protests.

In the capital, Tehran, videos circulating on social media on Wednesday appeared to show demonstrations in several neighborhoods and universities, as well as closed shops. (Int’l Monitoring Desk)

Iranian security forces opened fire at people who gathered at a cemetery in Mahsa Amini’s home town of Saqez on Wednesday to mark 40 days since she died in police custody, a witness said.

from Kongra Star/ ANHA/ etc..shared with thanks.. via thefreeonline

“The riot police shot mourners who gathered at the cemetery for Mahsa’s memorial ceremony … dozens have been arrested,” the witness said.

Demonstrations ignited by the 22-year-old’s death on September 16 have become one of the boldest challenges to the Islamic Republic’s clerical leadership since the 1979 revolution.

Ongoing rioting has been supported by the US and Israeli media and infiltration machines, giving the Irani authorities an excuse for heavy police state repression.

​​​​​​​Sherine Hassan: for an international women’s conference against authoritarian mindset

“all our activities and actions are aimed at forming a women’s conference at the level of the four parts of Kurdistan and the world, and to expand further in neighbouring countries with the aim of uniting our strength and bringing about radical changes, to build an equal society.”

Member of the Kongra Star Coordination of Afrin region, Sherine Hassan has explained that the Kongra Star is to foster women role at all levels in establishing women’s conference with a unified vision in confronting the authoritarian mentality and dictatorial regimes.

Continue reading “Police attack massive Mahsa Amini memorial/ Rojava Revolution spreading -Woman Life Freedom-“

TEHRAN: Iranian security forces have clashed with people taking part in a memorial for Mahsa Amini, according to a semi-official news agency, as thousands gathered in her hometown of Saqqez to mark 40 days since her death.

“A limited number of those present at Mahsa Amini’s memorial clashed with police forces on the outskirts of Saqqez and were dispersed,” ISNA news agency reported on Wednesday. “Following the scattered clashes, internet in Saqqez was cut off due to security considerations.”

Amini, a 22-year-old Kurdish woman, died in the capital, Tehran, on September 16 after being detained by the country’s morality police for allegedly wearing improper hijab. Her family have challenged a state investigation that blamed pre-existing conditions for her death which, it said, was not the result of Amini being hit.

The weeks-long protests first broke out in Saqqez, in the northwestern Kurdistan province. They have since spread quickly across the country, persisting amid severe internet restrictions that remain in place.

The 40th day since someone’s funeral, known as “chehelom”, holds cultural significance in Iran and religious importance for Shia Muslims.

On Wednesday, videos circulating on social media showed large crowds marching and driving towards the Aychi cemetery in Saqqez, where Amini was laid to rest.

Those gathered included people converging from other cities and appeared to number in the thousands. Many chanted “woman, life, freedom” and “freedom, freedom”, slogans that have been widely used in the demonstrations across Iran, as well as in solidarity protests that have been organised outside the country.

Continue reading “Clashes but no Massacre at massive Mahsa Amini memorial/ Rojava Revolution spreads -Woman Life Freedom-“

Just false reports of chemical attacks by the Assad regime were enough to cause a furore and unleash US Missile Attacks… But now the West and MSM shut up, intimidated perhaps by Erdogan’s usual blackmail. Turkey routinely massacres Kurdish resisters and civilians, in order, as usual, to boost fascist support by genocidal minority persecution, in NE Syria, N and NE Iraq and SE Turkey itself.

26 Oct 2022, – ANHA | HAWARNEWS | English and thefreeonline

The Health Body in Al Jazira region denounced in the chemical attacks by the Turkish occupation, calling on international forces to expose Turkish crimes in international courts.

On Wednesday, the Health Body issued a statement to the public over the Turkish attacks with internationally prohibited chemical weapons.

Kurdish guerrillas publish footage of chemical weapons victims

Dozens of members of civil and health unions and institutions in the region participated in the statement, which was read by the co-chair of the Health Authority in Al Jazira Region, Khaled Daoud.

NEWS 26 Oct 2022, Wed – 14:13 2022-10-26T14:13:00 QAMISHLO

The statement said: “Since a while, the Turkish occupation state has increased its brutal attacks on the People’s Defense Forces in the legitimate defense areas, using internationally prohibited weapons, and the echoes of these brutal attacks are escalating and in many parts of the world.

The statement continued, “The International Doctors Association for the Prevention of Nuclear Wars, which is based in Vienna, Austria, published a report via Reuters, during its visit to Iraq and the Kurdistan region, that all evidence confirms the Turkish army’s use of these internationally prohibited weapons, contrary to what the Turkish Armed Forces’ allegations claim that they did not use these weapons.” .

Pointing out that what was published by the Media Center of the People Defense Forces, including pictures and videos of the wounded fighters is irrefutable evidence.”

International silence over Turkey’s use of banned chemical weapons …

Continue reading “Evidence confirms Turkey’s obscene, illegal use of Chemical Weapons / West Ignores Crimes of NATO member – Al Jazira’s Health Body”